Used commonly to treat bullous disorders, such as pemphigus vulgaris, epidermolysis bullosa, and toxic epidermal necrolysis. Silver sulfadiazine (SSD) cream, known for its antibacterial effects when used as a dressing for extensive burn wounds, is When prescribing protracted wound care with SSD for blistering disorders. Hence we recommend that clinicians exercise caution In burn patients may be applicable to patients with bullous diseases. Renal insufficiency accelerates silver accumulation and thus toxicity.ĭata on silver toxicity in patients with primary blistering disorders is scarce however the literature regarding silver toxicity Toxicity has been well documented in burn patients. The beneficial antibacterial effect of SSD use is not without risk, as silver Management of erosions in bullous disorders. Silver sulfadiazine (SSD) cream, most known for its use in the treatment of extensive burn wounds, is commonly used in the These signs include pain, increasing redness or pus where this medicine is being used.Silver sulfadiazine therapy in widespread bullous disorders: Potential for toxicityĮmily M Mintz, Dornechia E George, Sylvia Hsu Dermatology Online Journal 14 (3): 19 Department of Dermatology, Baylor College of Medicine, Houston, TX, USA Abstract Seek medical attention if you see any signs of a serious infection. Do not take 2 doses of this medicine at one time.ĭo not share this medicine with anyone who has not been prescribed this medicine. If it is almost time for the next dose, do not take the missed dose. If you forget to take a dose on time, take it as soon as you remember. It is important that you keep taking each dose of this medicine on time even if you are feeling well. Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding. Symptoms of an allergic reaction can include trouble breathing, skin rash, itching, swelling, or severe dizziness.ĭo not use the medication any more than instructed.Ĭontact your doctor if you notice a change in the amount or darkening of your urine. Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine. Also tell them about any vitamins, herbal medicines, or anything else you take for your health. Include both prescription and over-the-counter medicines. Please tell your doctor and pharmacist about all the medicines you take. You may reapply the medicine during the day if the wound becomes dirty and needs to cleaned. If medicine gets in your eyes, rinse well with warm water. Wash your hands after using this medicine unless your hands are part of the area being treated.ĭo not touch your eyes, nose or mouth after handling the medicine. Wash your hands before and after handling this medicine. Use sunscreen lotion with SPF 15 or higher. Wash the medicine off your fingers after applying it.Īvoid prolonged or excessive sunlight exposure. This medicine should only be used on the skin.ĭo not apply other lotions, creams or gels to the same place you apply this medicine.Īvoid getting the medicine in the eyes, nose, or mouth. If some of the medicine rubs off, reapply it right away to make sure the wound is covered. Use fabric tape to hold the gauze in place.Īpply a thin layer to completely cover the wound. Use sterile gloves or a sterile applicator to apply the medicine.Īpply medicine directly to wound or onto a sterile gauze pad that is then applied to the wound. Wash the area first before applying medicine.
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